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Studies on 16α-Hydroxylation of Steroid Molecules and Regioselective Binding Mode in Homology-Modeled Cytochrome P450-2C11

We investigated the 16α-hydroxylation of steroid molecules and regioselective binding mode in homology-modeled cytochrome P450-2C11 to correlate the biological study with the computational molecular modeling. It revealed that there was a positive relationship between the observed inhibitory potencie...

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Detalles Bibliográficos
Autores principales: Ali, Hamed I., Yamada, Morio, Fujita, Yukihisa, Maeda, Mitsuko, Akaho, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970648/
https://www.ncbi.nlm.nih.gov/pubmed/27516905
http://dx.doi.org/10.1155/2011/918168