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Studies on 16α-Hydroxylation of Steroid Molecules and Regioselective Binding Mode in Homology-Modeled Cytochrome P450-2C11
We investigated the 16α-hydroxylation of steroid molecules and regioselective binding mode in homology-modeled cytochrome P450-2C11 to correlate the biological study with the computational molecular modeling. It revealed that there was a positive relationship between the observed inhibitory potencie...
Autores principales: | Ali, Hamed I., Yamada, Morio, Fujita, Yukihisa, Maeda, Mitsuko, Akaho, Eiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970648/ https://www.ncbi.nlm.nih.gov/pubmed/27516905 http://dx.doi.org/10.1155/2011/918168 |
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