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Protein Kinase RNA-Like Endoplasmic Reticulum Kinase-Mediated Bcl-2 Protein Phosphorylation Contributes to Evodiamine-Induced Apoptosis of Human Renal Cell Carcinoma Cells

We investigated the anticancer mechanism of evodiamine (EVO) against the viability of human A498 renal cell carcinoma (RCC) cells in vitro and in vivo. The in vitro study showed that EVO decreased the viability of A498 cells with the occurrence of apoptotic characteristics such as hypodiploid cells,...

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Detalles Bibliográficos
Autores principales:	Wu, Wen-Shin, Chien, Chih-Chiang, Chen, Yen-Chou, Chiu, Wen-Ta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970736/ https://www.ncbi.nlm.nih.gov/pubmed/27483435 http://dx.doi.org/10.1371/journal.pone.0160484

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