Cargando…

In Vivo Mouse Intervertebral Disc Degeneration Model Based on a New Histological Classification

Although human intervertebral disc degeneration can lead to several spinal diseases, its pathogenesis remains unclear. This study aimed to create a new histological classification applicable to an in vivo mouse intervertebral disc degeneration model induced by needle puncture. One hundred six mice w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ohnishi, Takashi, Sudo, Hideki, Iwasaki, Koji, Tsujimoto, Takeru, Ito, Yoichi M., Iwasaki, Norimasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970753/ https://www.ncbi.nlm.nih.gov/pubmed/27482708 http://dx.doi.org/10.1371/journal.pone.0160486

Ejemplares similares

Effects of Single Injection of Local Anesthetic Agents on Intervertebral Disc Degeneration: Ex Vivo and Long-Term In Vivo Experimental Study
por: Iwasaki, Koji, et al.
Publicado: (2014)

Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging
por: Ohnishi, Takashi, et al.
Publicado: (2019)

Causes of and Molecular Targets for the Treatment of Intervertebral Disc Degeneration: A Review
por: Ohnishi, Takashi, et al.
Publicado: (2022)

A Review: Methodologies to Promote the Differentiation of Mesenchymal Stem Cells for the Regeneration of Intervertebral Disc Cells Following Intervertebral Disc Degeneration
por: Ohnishi, Takashi, et al.
Publicado: (2023)

An acellular bioresorbable ultra-purified alginate gel promotes intervertebral disc repair: A preclinical proof-of-concept study
por: Tsujimoto, Takeru, et al.
Publicado: (2018)

Ultra-purified alginate gel implantation decreases inflammatory cytokine levels, prevents intervertebral disc degeneration, and reduces acute pain after discectomy
por: Ura, Katsuro, et al.
Publicado: (2021)

Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs
por: Ukeba, Daisuke, et al.
Publicado: (2020)

Biomaterials and Cell-Based Regenerative Therapies for Intervertebral Disc Degeneration with a Focus on Biological and Biomechanical Functional Repair: Targeting Treatments for Disc Herniation
por: Yamada, Katsuhisa, et al.
Publicado: (2022)

Global Identification of Genes Related to Nutrient Deficiency in Intervertebral Disc Cells in an Experimental Nutrient Deprivation Model
por: Sudo, Hideki, et al.
Publicado: (2013)

Cytotoxic Effects of the Radiocontrast Agent Iotrolan and Anesthetic Agents Bupivacaine and Lidocaine in Three-Dimensional Cultures of Human Intervertebral Disc Nucleus Pulposus Cells: Identification of the Apoptotic Pathways
por: Iwasaki, Koji, et al.
Publicado: (2014)

Combination of ultra-purified stem cells with an in situ-forming bioresorbable gel enhances intervertebral disc regeneration
por: Ukeba, Daisuke, et al.
Publicado: (2022)

Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration
por: Sano, Tomohiko, et al.
Publicado: (2019)

Histological Identification of Propionibacterium acnes in Nonpyogenic Degenerated Intervertebral Discs
por: Yuan, Ye, et al.
Publicado: (2017)

Intervertebral disc degeneration in warmblood horses: Histological and biochemical characterization
por: Bergmann, Wilhelmina, et al.
Publicado: (2022)

Degeneration of the intervertebral disc
por: Urban, Jill PG, et al.
Publicado: (2003)

Intradiscal injection of monosodium iodoacetate induces intervertebral disc degeneration in an experimental rabbit model
por: Sudo, Takao, et al.
Publicado: (2021)

Alterations in ECM signature underscore multiple sub-phenotypes of intervertebral disc degeneration
por: Ohnishi, Takashi, et al.
Publicado: (2020)

Epoxyeicosanoids prevent intervertebral disc degeneration in vitro and in vivo
por: Li, Jing, et al.
Publicado: (2016)

Anti-Inflammatory Effects of Adiponectin Receptor Agonist AdipoRon against Intervertebral Disc Degeneration
por: Ohnishi, Hiroki, et al.
Publicado: (2023)

Pathomechanism of intervertebral disc degeneration
por: Oichi, Takeshi, et al.
Publicado: (2020)

Treatment of Intervertebral Disc Degeneration
por: Xin, Jingguo, et al.
Publicado: (2022)

Macrophages and Intervertebral Disc Degeneration
por: Koroth, Jinsha, et al.
Publicado: (2023)

The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment
por: Sun, Zhen, et al.
Publicado: (2020)

Expression of Glial-Cell-Line-Derived Neurotrophic Factor Family Ligands in Human Intervertebral Discs
por: Iwasaki, Tatsuya, et al.
Publicado: (2023)

Significance of Immune-Related Genes in the Diagnosis and Classification of Intervertebral Disc Degeneration
por: Wu, Bo, et al.
Publicado: (2022)

Protective Effects of Growth Differentiation Factor-6 on the Intervertebral Disc: An In Vitro and In Vivo Study
por: Miyazaki, Kunihiko, et al.
Publicado: (2022)

Autophagy and mTOR signaling during intervertebral disc aging and degeneration
por: Yurube, Takashi, et al.
Publicado: (2020)

Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)

Effect of diminished flow in rabbit lumbar arteries on intervertebral disc matrix changes using MRI T2-mapping and histology
por: Imanishi, Takao, et al.
Publicado: (2019)

Gene Therapy Approach for Intervertebral Disc Degeneration: An Update
por: Takeoka, Yoshiki, et al.
Publicado: (2020)

Intervertebral Disc Biology: Genetic Basis of Disc Degeneration
por: Munir, Sabrina, et al.
Publicado: (2018)

Angiogenesis in the degeneration of the lumbar intervertebral disc
por: David, Gh, et al.
Publicado: (2010)

Intervertebral disc degeneration therapies in human
por: Richardson, Stephen M
Publicado: (2015)

Genetic factors in intervertebral disc degeneration
por: Feng, Yi, et al.
Publicado: (2016)

The Role of Adipokines in Intervertebral Disc Degeneration
por: Sharma, Anirudh
Publicado: (2018)

Molecular Mechanisms of Intervertebral Disc Degeneration
por: Rider, Sean M., et al.
Publicado: (2018)

Genetic Therapy for Intervertebral Disc Degeneration
por: Roh, Eun Ji, et al.
Publicado: (2021)

Cervical intervertebral disc degeneration and dizziness
por: Liu, Tang-Hua, et al.
Publicado: (2021)

The Proteolysis of ECM in Intervertebral Disc Degeneration
por: Liang, Huaizhen, et al.
Publicado: (2022)

The role of ferroptosis in intervertebral disc degeneration
por: Fan, Chunyang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_p3josuj68tf8fh9onadvk9sm3j