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Rapid signaling in distinct dopaminergic axons during locomotion and reward

Dopaminergic projections from the midbrain to striatum are critical for motor control, as their degeneration in Parkinson’s disease results in profound movement deficits. Paradoxically, most recording methods report rapid phasic dopamine signaling (~100ms bursts) to unpredicted rewards, with little...

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Detalles Bibliográficos
Autores principales: Howe, MW, Dombeck, DA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970879/
https://www.ncbi.nlm.nih.gov/pubmed/27398617
http://dx.doi.org/10.1038/nature18942

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