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Aging Shapes the Population-Mean and -Dispersion of Gene Expression in Human Brains

Human aging is associated with cognitive decline and an increased risk of neurodegenerative disease. Our objective for this study was to evaluate potential relationships between age and variation in gene expression across different regions of the brain. We analyzed the Genotype-Tissue Expression (GT...

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Detalles Bibliográficos
Autores principales: Brinkmeyer-Langford, Candice L., Guan, Jinting, Ji, Guoli, Cai, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971101/
https://www.ncbi.nlm.nih.gov/pubmed/27536236
http://dx.doi.org/10.3389/fnagi.2016.00183

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