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2-cyclohexylamino-5,8-dimethoxy-1,4-naphthoquinone inhibits LPS-induced BV2 microglial activation through MAPK/NF-kB signaling pathways

AIMS: To verify the effects of several 5,8-dimethoxy-1,4-naphthoquinone (DMNQ) derivatives on LPS-induced NO production, cellular ROS levels and cytokine expression in BV-2 microglial cells. MAIN METHODS: An MTT assay and FACS flow cytometry were performed to assess the cellular viability and apopto...

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Detalles Bibliográficos
Autores principales:	Sun, Hu-Nan, Shen, Gui-Nan, Jin, Yong-Zhe, Jin, Yu, Han, Ying-Hao, Feng, Li, Liu, Lei, Jin, Mei-Hua, Luo, Ying-Hua, Kwon, Tea-Ho, Cui, Yu-Dong, Jin, Cheng-Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971128/ https://www.ncbi.nlm.nih.gov/pubmed/27512726 http://dx.doi.org/10.1016/j.heliyon.2016.e00132

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