Large tumor suppressors 1 and 2 regulate Aurora-B through phosphorylation of INCENP to ensure completion of cytokinesis

The tumor suppressor kinases LATS1 and LATS2 (LATS1/2) regulate not only organ size through the Hippo signaling pathway, but also cell-cycle checkpoints and apoptosis via other signaling cascades. We previously reported that LATS1/2 localize to the mitotic apparatus, where they are involved in the p...

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Detalles Bibliográficos
Autores principales: Yabuta, Norikazu, Yoshida, Kaori, Mukai, Satomi, Kato, Yorika, Torigata, Kosuke, Nojima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971130/
https://www.ncbi.nlm.nih.gov/pubmed/27512725
http://dx.doi.org/10.1016/j.heliyon.2016.e00131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971130/
https://www.ncbi.nlm.nih.gov/pubmed/27512725
http://dx.doi.org/10.1016/j.heliyon.2016.e00131

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