Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi

Chagas disease is a neglected tropical disease caused by the flagellated protozoan Trypanosoma cruzi. The current drugs used to treat this disease have limited efficacy and produce severe side effects. Quinolines, nitrogen heterocycle compounds that form complexes with heme, have a broad spectrum of...

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Detalles Bibliográficos
Autores principales: Lechuga, Guilherme Curty, Borges, Júlio Cesar, Calvet, Claudia Magalhães, de Araújo, Humberto Pinheiro, Zuma, Aline Araujo, do Nascimento, Samara Braga, Motta, Maria Cristina Machado, Bernardino, Alice Maria Rolim, Pereira, Mirian Claudia de Souza, Bourguignon, Saulo Cabral
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971285/
https://www.ncbi.nlm.nih.gov/pubmed/27490082
http://dx.doi.org/10.1016/j.ijpddr.2016.07.001

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