Potential of Inducible Nitric Oxide Synthase as a Therapeutic Target for Allergen-Induced Airway Hyperresponsiveness: A Critical Connection to Nitric Oxide Levels and PARP Activity

Although expression of inducible NO synthase (iNOS) in the lungs of asthmatics and associated nitrosative damage are established, iNOS failed as a therapeutic target for blocking airway hyperresponsiveness (AHR) and inflammation in asthmatics. This dichotomy calls for better strategies with which th...

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Detalles Bibliográficos
Autores principales: Ibba, Salome' V., Ghonim, Mohamed A., Pyakurel, Kusma, Lammi, Matthew R., Mishra, Anil, Boulares, A. Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971330/
https://www.ncbi.nlm.nih.gov/pubmed/27524861
http://dx.doi.org/10.1155/2016/1984703

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