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Design and characterization of a polyamine derivative inhibiting the expression of type III secretion system in Pseudomonas aeruginosa

The type III secretion system (TTSS) of Pseudomonas aeruginosa is a key virulence determinant for infection of eukaryotic hosts. Based on the findings that spermidine-mediated host-pathogen signalling is important for activation of type III secretion systems (TTSS), in this study, we designed, synth...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Liu, Xiaoling, Wang, Jing, Zhou, Jianuan, Cui, Zining, Zhang, Lian-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971474/
https://www.ncbi.nlm.nih.gov/pubmed/27484745
http://dx.doi.org/10.1038/srep30949