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Design and characterization of a polyamine derivative inhibiting the expression of type III secretion system in Pseudomonas aeruginosa
The type III secretion system (TTSS) of Pseudomonas aeruginosa is a key virulence determinant for infection of eukaryotic hosts. Based on the findings that spermidine-mediated host-pathogen signalling is important for activation of type III secretion systems (TTSS), in this study, we designed, synth...
Autores principales: | Wang, Chao, Liu, Xiaoling, Wang, Jing, Zhou, Jianuan, Cui, Zining, Zhang, Lian-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971474/ https://www.ncbi.nlm.nih.gov/pubmed/27484745 http://dx.doi.org/10.1038/srep30949 |
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