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Osteopontin Deficiency Alters Biliary Homeostasis and Protects against Gallstone Formation

The precipitation of excess biliary cholesterol as solid crystals is a prerequisite for cholesterol gallstone formation, which occurs due to disturbed biliary homeostasis. Biliary homeostasis is regulated by an elaborate network of genes in hepatocytes. If unmanaged, the cholesterol crystals will ag...

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Detalles Bibliográficos
Autores principales:	Lin, Jing, Shao, Wei-qing, Chen, Zong-you, Zhu, Wen-wei, Lu, Lu, Cai, Duan, Qin, Lun-xiu, Jia, Hu-liang, Lu, Ming, Chen, Jin-hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971489/ https://www.ncbi.nlm.nih.gov/pubmed/27484115 http://dx.doi.org/10.1038/srep30215

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