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The Thyroid Hormone Receptors Inhibit Hepatic Interleukin-6 Signaling During Endotoxemia
Decreased thyroidal hormone production is found during lipopolysaccharide (LPS)-induced endotoxic shock in animals as well as in critically ill patients. Here we studied the role of the thyroid hormone receptors (TRs) in activation of STAT3, NF-κB and ERK, which play a key role in the response to in...
Autores principales: | Contreras-Jurado, Constanza, Alonso-Merino, Elvira, Saiz-Ladera, Cristina, Valiño, Arturo José, Regadera, Javier, Alemany, Susana, Aranda, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971531/ https://www.ncbi.nlm.nih.gov/pubmed/27484112 http://dx.doi.org/10.1038/srep30990 |
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