Muscleblind-like 3 deficit results in a spectrum of age-associated pathologies observed in myotonic dystrophy

Myotonic dystrophy type I (DM1) exhibits distinctive disease specific phenotypes and the accelerated onset of a spectrum of age-associated pathologies. In DM1, dominant effects of expanded CUG repeats result in part from the inactivation of the muscleblind-like (MBNL) proteins. To test the role of M...

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Detalles Bibliográficos
Autores principales: Choi, Jongkyu, Dixon, Donald M., Dansithong, Warunee, Abdallah, Walid F., Roos, Kenneth P., Jordan, Maria C., Trac, Brandon, Lee, Han Shin, Comai, Lucio, Reddy, Sita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971533/
https://www.ncbi.nlm.nih.gov/pubmed/27484195
http://dx.doi.org/10.1038/srep30999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971533/
https://www.ncbi.nlm.nih.gov/pubmed/27484195
http://dx.doi.org/10.1038/srep30999

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