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Pharmacokinetics and Metabolism of Cyadox and Its Main Metabolites in Beagle Dogs Following Oral, Intramuscular, and Intravenous Administration
Cyadox (Cyx) is an antibacterial drug of the quinoxaline group that exerts markedly lower toxicity in animals, compared to its congeners. Here, the pharmacokinetics and metabolism of Cyx after oral (PO), intramuscular (IM), and intravenous (IV) routes of administration were studied to establish safe...
Autores principales: | Sattar, Adeel, Xie, Shuyu, Huang, Lingli, Iqbal, Zahid, Qu, Wei, Shabbir, Muhammad A., Pan, Yuanhu, Hussain, Hafiz I., Chen, Dongmei, Tao, Yanfei, Liu, Zhenli, Iqbal, Mujahid, Yuan, Zonghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971586/ https://www.ncbi.nlm.nih.gov/pubmed/27536243 http://dx.doi.org/10.3389/fphar.2016.00236 |
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