The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis

BACKGROUND: Real-time PCR (qPCR) based methods, such as the Xpert MTB/RIF, are increasingly being used to diagnose tuberculosis (TB). While qualitative methods are adequate for diagnosis, the therapeutic monitoring of TB patients requires quantitative methods currently performed using smear microsco...

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Detalles Bibliográficos
Autores principales: Devonshire, Alison S., O’Sullivan, Denise M., Honeyborne, Isobella, Jones, Gerwyn, Karczmarczyk, Maria, Pavšič, Jernej, Gutteridge, Alice, Milavec, Mojca, Mendoza, Pablo, Schimmel, Heinz, Van Heuverswyn, Fran, Gorton, Rebecca, Cirillo, Daniela Maria, Borroni, Emanuele, Harris, Kathryn, Barnard, Marinus, Heydenrych, Anthenette, Ndusilo, Norah, Wallis, Carole L., Pillay, Keshree, Barry, Thomas, Reddington, Kate, Richter, Elvira, Mozioğlu, Erkan, Akyürek, Sema, Yalçınkaya, Burhanettin, Akgoz, Muslum, Žel, Jana, Foy, Carole A., McHugh, Timothy D., Huggett, Jim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971652/
https://www.ncbi.nlm.nih.gov/pubmed/27487852
http://dx.doi.org/10.1186/s12879-016-1696-7

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