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Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2

BACKGROUND: Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis, and lncRNA taurine-upregulated gene 1 (TUG1) has been proven to be associated with several human cancers. However, the mechanisms of TUG1-involved regulation remain largely unknown. METHODS: We examined the expressions of...

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Detalles Bibliográficos
Autores principales: Lin, Pei-Chin, Huang, Hsien-Da, Chang, Chun-Chi, Chang, Ya-Sian, Yen, Ju-Chen, Lee, Chien-Chih, Chang, Wen-Hsin, Liu, Ta-Chih, Chang, Jan-Gowth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971684/
https://www.ncbi.nlm.nih.gov/pubmed/27485439
http://dx.doi.org/10.1186/s12885-016-2569-6