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Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model
Astrocytes are key participants in various aspects of brain development and function, many of which are executed via secreted proteins. Defects in astrocyte signaling are implicated in neurodevelopmental disorders characterized by abnormal neural circuitry such as Fragile X syndrome (FXS). In animal...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971702/ https://www.ncbi.nlm.nih.gov/pubmed/27485117 http://dx.doi.org/10.1186/s13041-016-0256-9 |