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Emodin enhances cisplatin-induced cytotoxicity in human bladder cancer cells through ROS elevation and MRP1 downregulation

BACKGROUND: Chemoresistance is one of the most leading causes for tumor progression and recurrence of bladder cancer. Reactive oxygen species (ROS) plays a key role in the chemosensitivity of cancer cells. In the present study, emodin (1,3,8-trihydroxy-6-methylanthraquinone) was applied as a ROS gen...

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Detalles Bibliográficos
Autores principales:	Li, Xinxing, Wang, Haolu, Wang, Juan, Chen, Yuying, Yin, Xiaobin, Shi, Guiying, Li, Hui, Hu, Zhiqian, Liang, Xiaowen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971704/ https://www.ncbi.nlm.nih.gov/pubmed/27485374 http://dx.doi.org/10.1186/s12885-016-2640-3

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