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Variant detection and runs of homozygosity in next generation sequencing data elucidate the genetic background of Lundehund syndrome
BACKGROUND: The Lundehund is a highly specialized breed characterized by a unique flexibility of the joints and polydactyly in all four limbs. The extremely small population size and high inbreeding has promoted a high frequency of diseased dogs affected by the Lundehund syndrome (LS), a severe gast...
Autores principales: | Metzger, Julia, Pfahler, Sophia, Distl, Ottmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971756/ https://www.ncbi.nlm.nih.gov/pubmed/27485430 http://dx.doi.org/10.1186/s12864-016-2844-6 |
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