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Sperm is epigenetically programmed to regulate gene transcription in embryos
For a long time, it has been assumed that the only role of sperm at fertilization is to introduce the male genome into the egg. Recently, ideas have emerged that the epigenetic state of the sperm nucleus could influence transcription in the embryo. However, conflicting reports have challenged the ex...
Autores principales: | Teperek, Marta, Simeone, Angela, Gaggioli, Vincent, Miyamoto, Kei, Allen, George E., Erkek, Serap, Kwon, Taejoon, Marcotte, Edward M., Zegerman, Philip, Bradshaw, Charles R., Peters, Antoine H.F.M., Gurdon, John B., Jullien, Jerome |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971762/ https://www.ncbi.nlm.nih.gov/pubmed/27034506 http://dx.doi.org/10.1101/gr.201541.115 |
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