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TBR1 regulates autism risk genes in the developing neocortex

Exome sequencing studies have identified multiple genes harboring de novo loss-of-function (LoF) variants in individuals with autism spectrum disorders (ASD), including TBR1, a master regulator of cortical development. We performed ChIP-seq for TBR1 during mouse cortical neurogenesis and show that T...

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Detalles Bibliográficos
Autores principales:	Notwell, James H., Heavner, Whitney E., Darbandi, Siavash Fazel, Katzman, Sol, McKenna, William L., Ortiz-Londono, Christian F., Tastad, David, Eckler, Matthew J., Rubenstein, John L.R., McConnell, Susan K., Chen, Bin, Bejerano, Gill
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971772/ https://www.ncbi.nlm.nih.gov/pubmed/27325115 http://dx.doi.org/10.1101/gr.203612.115

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