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Differential Biphasic Transcriptional Host Response Associated with Coevolution of Hemagglutinin Quasispecies of Influenza A Virus

Severe influenza associated with strong symptoms and lung inflammation can be caused by intra-host evolution of quasispecies with aspartic acid or glycine in hemagglutinin position 222 (HA-222D/G; H1 numbering). To gain insights into the dynamics of host response to this coevolution and to identify...

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Detalles Bibliográficos
Autores principales: Manchanda, Himanshu, Seidel, Nora, Blaess, Markus F., Claus, Ralf A., Linde, Joerg, Slevogt, Hortense, Sauerbrei, Andreas, Guthke, Reinhard, Schmidtke, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971777/
https://www.ncbi.nlm.nih.gov/pubmed/27536272
http://dx.doi.org/10.3389/fmicb.2016.01167