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Higher preoperative serum levels of PD‐L1 and B7‐H4 are associated with invasive and metastatic potential and predictable for poor response to VEGF‐targeted therapy and unfavorable prognosis of renal cell carcinoma

Renal cell carcinoma (RCC) is an immunogenic and proangiogenic cancer. Although antivascular endothelial growth factor (VEGF) therapies achieve impressive responses in some patients, many tumors eventually develop resistance to such therapy. The B7 family molecules such as CTLA‐4, PD‐1, and PD‐L1 ar...

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Detalles Bibliográficos
Autores principales:	Fukuda, Takehiko, Kamai, Takao, Masuda, Akinori, Nukui, Akinori, Abe, Hideyuki, Arai, Kyoko, Yoshida, Ken‐Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Clinical Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971909/ https://www.ncbi.nlm.nih.gov/pubmed/27292320 http://dx.doi.org/10.1002/cam4.754

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