Cargando…

Viral-mediated Ntf3 overexpression disrupts innervation and hearing in nondeafened guinea pig cochleae

Synaptopathy in the cochlea occurs when the connection between inner hair cells and the auditory nerve is disrupted, leading to impaired hearing and nerve degeneration. Experiments using transgenic mice have shown that overexpression of NT3 by supporting cells repairs synaptopathy caused by overstim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Min Young, Kurioka, Takaomi, Nelson, Megan M, Prieskorn, Diane M, Swiderski, Donald L, Takada, Yohei, Beyer, Lisa A, Raphael, Yehoash
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972090/ https://www.ncbi.nlm.nih.gov/pubmed/27525291 http://dx.doi.org/10.1038/mtm.2016.52

Ejemplares similares

Differential Effects of AAV.BDNF and AAV.Ntf3 in the Deafened Adult Guinea Pig Ear
por: Budenz, Cameron L., et al.
Publicado: (2015)

Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea
por: Lee, Sungsu, et al.
Publicado: (2020)

Survival of human embryonic stem cells implanted in the guinea pig auditory epithelium
por: Young Lee, Min, et al.
Publicado: (2017)

Protein transduction therapy into cochleae via the round window niche in guinea pigs
por: Takeda, Hiroki, et al.
Publicado: (2016)

Gene transfer using bovine adeno-associated virus in the guinea pig cochlea
por: Shibata, Seiji B., et al.
Publicado: (2009)

Ototoxicity-induced loss of hearing and inner hair cells is attenuated by HSP70 gene transfer
por: Takada, Yohei, et al.
Publicado: (2015)

Corrigendum: ACEMg Diet Supplement Modifies Progression of Hereditary Deafness
por: Green, Kari L., et al.
Publicado: (2016)

ACEMg Diet Supplement Modifies Progression of Hereditary Deafness
por: Green, Kari L., et al.
Publicado: (2016)

Hearing loss in mice with disruption of auditory epithelial patterning in the cochlea
por: Katsunuma, Sayaka, et al.
Publicado: (2022)

GJB2 gene therapy and conditional deletion reveal developmental stage-dependent effects on inner ear structure and function
por: Guo, Jingying, et al.
Publicado: (2021)

Volatility of molten salts [Ph(4)P][NTf(2)] and Cs[NTf(2)]
por: Zaitsau, Dzmitry H., et al.
Publicado: (2020)

Effect of nicotine on the structure of cochlea of guinea pigs
por: Abdel-Hafez, Amel M. M., et al.
Publicado: (2014)

Ototoxicity of acetic acid on the guinea pig cochlea
por: Yamano, Takafumi, et al.
Publicado: (2015)

Use of scanning electron microscopy in the cochlea of guinea pigs
por: Iha, Luiz César Nakao, et al.
Publicado: (2019)

Effects of the Conductive Component of Hearing Loss on Speech Discrimination Ability
por: Kurioka, Takaomi, et al.
Publicado: (2020)

Gata3 is required for the functional maturation of inner hair cells and their innervation in the mouse cochlea
por: Bardhan, Tanaya, et al.
Publicado: (2019)

Sex Genotyping of Archival Fixed and Immunolabeled Guinea Pig Cochleas
por: Depreux, Frédéric F., et al.
Publicado: (2018)

Transient Conductive Hearing Loss Regulates Cross-Modal VGLUT Expression in the Cochlear Nucleus of C57BL/6 Mice
por: Kurioka, Takaomi, et al.
Publicado: (2020)

Hearing Protection Outcomes of Analog Electrode Arrays Coated with Different Drug-Eluting Polymer Films Implanted into Guinea Pig Cochleae
por: Huang, Yuyu, et al.
Publicado: (2021)

Hearing Protection Outcomes of Analog Electrode Arrays Coated with Different Drug-Eluting Polymer Films Implanted into Guinea Pig Cochleae [Corrigendum]
Publicado: (2021)

ROS Scavenger, Ebselen, Has No Preventive Effect in New Hearing Loss Model Using a Cholesterol-Chelating Agent
por: Lee, Min Young, et al.
Publicado: (2019)

Distribution and change of peroxynitrite in the guinea pig cochlea following noise exposure
por: Han, Wei-Ju, et al.
Publicado: (2018)

Imaging Bioluminescent Exogenous Stem Cells in the Intact Guinea Pig Cochlea
por: Schomann, Timo, et al.
Publicado: (2019)

Vibration direction sensitivity of the cochlea with bone conduction stimulation in guinea pigs
por: Zhao, Mingduo, et al.
Publicado: (2021)

Aldosterone inhibits Dot1l expression in guinea pig cochlea
por: Zhong, Shixun, et al.
Publicado: (2023)

Clinical features and hearing prognosis of idiopathic sudden sensorineural hearing loss in patients undergoing hemodialysis: A retrospective study
por: Yamamoto, Kengo, et al.
Publicado: (2021)

Filling out the structural map of the NTF2-like superfamily
por: Eberhardt, Ruth Y, et al.
Publicado: (2013)

NTF3 Correlates With Prognosis and Immune Infiltration in Hepatocellular Carcinoma
por: Liu, Rongqiang, et al.
Publicado: (2021)

Long-term administration of vitamin B12 and adenosine triphosphate for idiopathic sudden sensorineural hearing loss: a retrospective study
por: Kurioka, Takaomi, et al.
Publicado: (2020)

Clinical Characteristics and Corticosteroid Responses of Acoustic Neuroma Treated as Idiopathic Sudden Sensorineural Hearing Loss
por: Nakamura, Yoshinari, et al.
Publicado: (2023)

Is repetitive systemic corticosteroid therapy effective for idiopathic sudden sensorineural hearing loss? a retrospective study
por: Yamamoto, Kengo, et al.
Publicado: (2023)

Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea
por: Oiticica, Jeanne, et al.
Publicado: (2010)

Grxcr2 is required for stereocilia morphogenesis in the cochlea
por: Avenarius, Matthew R., et al.
Publicado: (2018)

USH2A Gene Mutations in Rabbits Lead to Progressive Retinal Degeneration and Hearing Loss
por: Nguyen, Van Phuc, et al.
Publicado: (2023)

Gene Expression Pattern after Insertion of Dexamethasone-Eluting Electrode into the Guinea Pig Cochlea
por: Takumi, Yutaka, et al.
Publicado: (2014)

Ribbon Synapse Plasticity in the Cochleae of Guinea Pigs after Noise-Induced Silent Damage
por: Shi, Lijuan, et al.
Publicado: (2013)

Analysis of the Damage Mechanism Related to CO(2) Laser Cochleostomy on Guinea Pig Cochlea
por: Liu, Xiang, et al.
Publicado: (2016)

Regenerated hair cells in the neonatal cochlea are innervated and the majority co-express markers of both inner and outer hair cells
por: Heuermann, Mitchell L., et al.
Publicado: (2022)

Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing
por: Buniello, Annalisa, et al.
Publicado: (2016)

Mammalian cochlea as a physics guided evolution-optimized hearing sensor
por: Lorimer, Tom, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rcbi3jib823465c7dd3jgotehp