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HMGB1: The metabolic weapon in the arsenal of NK cells

Targeting tumor glycolysis would hit the main energy source of cancer. We show that natural killer (NK) cells pursue this strategy by employing high mobility group box 1 (HMGB1) protein—a well-known proinflammatory cytokine—to specifically target glycolysis in cancer cells. This opens up new perspec...

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Detalles Bibliográficos
Autores principales:	Cerwenka, Adelheid, Kopitz, Jürgen, Schirmacher, Peter, Roth, Wilfried, Gdynia, Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972106/ https://www.ncbi.nlm.nih.gov/pubmed/27652323 http://dx.doi.org/10.1080/23723556.2016.1175538

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