Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature

Chronic stress drives cancer progression, but the routes of metastasis are unclear. We recently demonstrated that chronic stress activates a neural-inflammatory signaling axis to remodel lymphatic vasculature and increase lymph flow. This unanticipated crosstalk between stress and the lymphatic syst...

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Detalles Bibliográficos
Autores principales: Le, Caroline P., Sloan, Erica K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972108/
https://www.ncbi.nlm.nih.gov/pubmed/27652324
http://dx.doi.org/10.1080/23723556.2016.1177674
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author Le, Caroline P.
Sloan, Erica K.
author_facet Le, Caroline P.
Sloan, Erica K.
author_sort Le, Caroline P.
collection PubMed
description Chronic stress drives cancer progression, but the routes of metastasis are unclear. We recently demonstrated that chronic stress activates a neural-inflammatory signaling axis to remodel lymphatic vasculature and increase lymph flow. This unanticipated crosstalk between stress and the lymphatic system provides pathways of tumor cell dissemination and accelerates metastasis.
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spelling pubmed-49721082017-05-31 Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature Le, Caroline P. Sloan, Erica K. Mol Cell Oncol Author's View Chronic stress drives cancer progression, but the routes of metastasis are unclear. We recently demonstrated that chronic stress activates a neural-inflammatory signaling axis to remodel lymphatic vasculature and increase lymph flow. This unanticipated crosstalk between stress and the lymphatic system provides pathways of tumor cell dissemination and accelerates metastasis. Taylor & Francis 2016-05-31 /pmc/articles/PMC4972108/ /pubmed/27652324 http://dx.doi.org/10.1080/23723556.2016.1177674 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Le, Caroline P.
Sloan, Erica K.
Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature
title Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature
title_full Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature
title_fullStr Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature
title_full_unstemmed Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature
title_short Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature
title_sort stress-driven lymphatic dissemination: an unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972108/
https://www.ncbi.nlm.nih.gov/pubmed/27652324
http://dx.doi.org/10.1080/23723556.2016.1177674
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