Cargando…
The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6
Follicular T helper (Tfh) cells are key regulators of the germinal center reaction and long‐term humoral immunity. Tfh cell differentiation requires the sustained expression of the transcriptional repressor Bcl6; however, its regulation in CD4(+) T cells is incompletely understood. Here, we report t...
Autores principales: | Stauss, Dennis, Brunner, Cornelia, Berberich‐Siebelt, Friederike, Höpken, Uta E, Lipp, Martin, Müller, Gerd |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972135/ https://www.ncbi.nlm.nih.gov/pubmed/26957522 http://dx.doi.org/10.15252/embj.201591459 |
Ejemplares similares
-
Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression
por: Vaeth, Martin, et al.
Publicado: (2014) -
Bob1 limits cellular frequency of T‐follicular helper cells
por: Yamashita, Keiji, et al.
Publicado: (2016) -
T Cell Specific BOB.1/OBF.1 Expression Promotes Germinal Center Response and T Helper Cell Differentiation
por: Betzler, Annika C., et al.
Publicado: (2022) -
Btk expression is controlled by Oct and BOB.1/OBF.1
por: Brunner, Cornelia, et al.
Publicado: (2006) -
Bcl6 expression specifies the T follicular helper cell program in vivo
por: Liu, Xindong, et al.
Publicado: (2012)