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Natalizumab Affects T-Cell Phenotype in Multiple Sclerosis: Implications for JCV Reactivation

The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV) and development of progressive multifocal leuk...

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Detalles Bibliográficos
Autores principales: Iannetta, Marco, Zingaropoli, Maria Antonella, Bellizzi, Anna, Morreale, Manuela, Pontecorvo, Simona, D’Abramo, Alessandra, Oliva, Alessandra, Anzivino, Elena, Lo Menzo, Sara, D’Agostino, Claudia, Mastroianni, Claudio Maria, Millefiorini, Enrico, Pietropaolo, Valeria, Francia, Ada, Vullo, Vincenzo, Ciardi, Maria Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972347/
https://www.ncbi.nlm.nih.gov/pubmed/27486658
http://dx.doi.org/10.1371/journal.pone.0160277

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