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Natalizumab Affects T-Cell Phenotype in Multiple Sclerosis: Implications for JCV Reactivation
The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV) and development of progressive multifocal leuk...
Autores principales: | Iannetta, Marco, Zingaropoli, Maria Antonella, Bellizzi, Anna, Morreale, Manuela, Pontecorvo, Simona, D’Abramo, Alessandra, Oliva, Alessandra, Anzivino, Elena, Lo Menzo, Sara, D’Agostino, Claudia, Mastroianni, Claudio Maria, Millefiorini, Enrico, Pietropaolo, Valeria, Francia, Ada, Vullo, Vincenzo, Ciardi, Maria Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972347/ https://www.ncbi.nlm.nih.gov/pubmed/27486658 http://dx.doi.org/10.1371/journal.pone.0160277 |
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