Cargando…
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo
NK cells are important antiviral effectors, highly enriched in the liver, with the potential to regulate immunopathogenesis in persistent viral infections. Here we examined whether changes in the NK pool are induced when patients with eAg-positive CHB are ‘primed’ with PegIFNα and importantly, wheth...
Autores principales: | Gill, Upkar S., Peppa, Dimitra, Micco, Lorenzo, Singh, Harsimran D., Carey, Ivana, Foster, Graham R., Maini, Mala K., Kennedy, Patrick T. F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972354/ https://www.ncbi.nlm.nih.gov/pubmed/27487232 http://dx.doi.org/10.1371/journal.ppat.1005788 |
Ejemplares similares
-
Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion
por: Peppa, Dimitra, et al.
Publicado: (2013) -
NK Cells: A Double-Edged Sword in Chronic Hepatitis B Virus Infection
por: Maini, Mala K., et al.
Publicado: (2013) -
The Third Signal Cytokine IL-12 Rescues the Anti-Viral Function of Exhausted HBV-Specific CD8 T Cells
por: Schurich, Anna, et al.
Publicado: (2013) -
Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection
por: Peppa, Dimitra, et al.
Publicado: (2010) -
TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis
por: Singh, Harsimran D., et al.
Publicado: (2017)