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Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids

PURPOSE: Variations in mitochondrial DNA (mtDNA) and abnormalities in the complement pathways have been implicated in the pathogenesis of age-related macular degeneration (AMD). This study was designed to determine the effects of mtDNA from AMD subjects on the complement pathway. METHODS: Transmitoc...

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Detalles Bibliográficos
Autores principales:	Nashine, Sonali, Chwa, Marilyn, Kazemian, Mina, Thaker, Kunal, Lu, Stephanie, Nesburn, Anthony, Kuppermann, Baruch D., Kenney, M. Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972370/ https://www.ncbi.nlm.nih.gov/pubmed/27486856 http://dx.doi.org/10.1371/journal.pone.0159828

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