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A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors
Thymic T-cell development is initiated from bone marrow-derived multi-potent thymus seeding progenitors (TSPs). During the early stages of thymocyte differentiation progenitors become T-cell restricted. However, the cellular environments supporting these critical initial stages of T-cell development...
Autores principales: | Buono, Mario, Facchini, Raffaella, Matsuoka, Sahoko, Thongjuea, Supat, Waithe, Dominique, Luis, Tiago C., Giustacchini, Alice, Besmer, Peter, Mead, Adam J., Jacobsen, Sten Eirik W., Nerlov, Claus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972409/ https://www.ncbi.nlm.nih.gov/pubmed/26780297 http://dx.doi.org/10.1038/ncb3299 |
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