Pancreatic Fibroblasts Stimulate the Motility of Pancreatic Cancer Cells through IGF1/IGF1R Signaling under Hypoxia

Pancreatic ductal adenocarcinoma (PDAC) is characterized by its hypovascularity, with an extremely poor prognosis because of its highly invasive nature. PDAC proliferates with abundant stromal cells, suggesting that its invasive activity might be controlled by intercellular interactions between canc...

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Detalles Bibliográficos
Autores principales: Hirakawa, Toshiki, Yashiro, Masakazu, Doi, Yosuke, Kinoshita, Haruhito, Morisaki, Tamami, Fukuoka, Tatsunari, Hasegawa, Tsuyoshi, Kimura, Kenjiro, Amano, Ryosuke, Hirakawa, Kosei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972430/
https://www.ncbi.nlm.nih.gov/pubmed/27487118
http://dx.doi.org/10.1371/journal.pone.0159912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972430/
https://www.ncbi.nlm.nih.gov/pubmed/27487118
http://dx.doi.org/10.1371/journal.pone.0159912

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