V(2)A(2)lidating TRP channel heteromers

Transient receptor potential (TRP) ion channels play a key role in sensing environmental and endogenous stimuli. Among sensory neurons, different TRP channels are widely expressed, and their expression profiles overlap. Although many TRP channels are homotetramers, we have shown that a functional te...

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Detalles Bibliográficos
Autores principales: Fischer, Michael JM, Edwardson, J Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Discovery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972508/
https://www.ncbi.nlm.nih.gov/pubmed/27580567
http://dx.doi.org/10.4161/temp.29548
Descripción
Sumario:Transient receptor potential (TRP) ion channels play a key role in sensing environmental and endogenous stimuli. Among sensory neurons, different TRP channels are widely expressed, and their expression profiles overlap. Although many TRP channels are homotetramers, we have shown that a functional tetrameric TRP channel can contain two types of monomers.

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