Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications

The evolution of pediatric solid tumors is poorly understood. There is conflicting evidence of intra-tumor genetic homogeneity vs. heterogeneity (ITGH) in a small number of studies in pediatric solid tumors. A number of copy number aberrations (CNA) are proposed as prognostic biomarkers to stratify...

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Detalles Bibliográficos
Autores principales: Cresswell, George D., Apps, John R., Chagtai, Tasnim, Mifsud, Borbala, Bentley, Christopher C., Maschietto, Mariana, Popov, Sergey D., Weeks, Mark E., Olsen, Øystein E., Sebire, Neil J., Pritchard-Jones, Kathy, Luscombe, Nicholas M., Williams, Richard D., Mifsud, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972528/
https://www.ncbi.nlm.nih.gov/pubmed/27333041
http://dx.doi.org/10.1016/j.ebiom.2016.05.029

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