v-SNARE transmembrane domains function as catalysts for vesicle fusion

Vesicle fusion is mediated by an assembly of SNARE proteins between opposing membranes, but it is unknown whether transmembrane domains (TMDs) of SNARE proteins serve mechanistic functions that go beyond passive anchoring of the force-generating SNAREpin to the fusing membranes. Here, we show that c...

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Detalles Bibliográficos
Autores principales: Dhara, Madhurima, Yarzagaray, Antonio, Makke, Mazen, Schindeldecker, Barbara, Schwarz, Yvonne, Shaaban, Ahmed, Sharma, Satyan, Böckmann, Rainer A, Lindau, Manfred, Mohrmann, Ralf, Bruns, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972536/
https://www.ncbi.nlm.nih.gov/pubmed/27343350
http://dx.doi.org/10.7554/eLife.17571

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