Diagnostic Molecular Mycobacteriology in Regions With Low Tuberculosis Endemicity: Combining Real-time PCR Assays for Detection of Multiple Mycobacterial Pathogens With Line Probe Assays for Identification of Resistance Mutations

Molecular assays have not yet been able to replace time-consuming culture-based methods in clinical mycobacteriology. Using 6875 clinical samples and a study period of 35 months we evaluated the use of PCR-based assays to establish a diagnostic workflow with a fast time-to-result of 1–2 days, for 1....

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Detalles Bibliográficos
Autores principales: Deggim-Messmer, Vanessa, Bloemberg, Guido V., Ritter, Claudia, Voit, Antje, Hömke, Rico, Keller, Peter M., Böttger, Erik C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972562/
https://www.ncbi.nlm.nih.gov/pubmed/27333026
http://dx.doi.org/10.1016/j.ebiom.2016.06.016

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