Nucleation of platelets with bloodborne pathogens on Kupffer cell precedes other innate immunity and contributes to bacterial clearance

Using intravital imaging of the liver, we unveil a collaborative role for platelets with Kupffer cells (KCs) in eradicating bloodborne bacterial infections. Under basal conditions, platelets via glycoprotein Ib (GPIb) formed transient “touch-and-go” interactions with von Willebrand factor (vWF) cons...

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Detalles Bibliográficos
Autores principales: Wong, Connie H. Y., Jenne, Craig N., Petri, Björn, Chrobok, Navina L., Kubes, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972575/
https://www.ncbi.nlm.nih.gov/pubmed/23770641
http://dx.doi.org/10.1038/ni.2631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972575/
https://www.ncbi.nlm.nih.gov/pubmed/23770641
http://dx.doi.org/10.1038/ni.2631

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