Free backbone carbonyls mediate rhodopsin activation

Conserved prolines in the transmembrane helices of G protein-coupled receptors (GPCRs) are often considered to function as hinges that divide the helix into two segments capable of independent motion. Depending on their potential to hydrogen-bond, the free C=O groups associated with these prolines c...

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Detalles Bibliográficos
Autores principales: Kimata, Naoki, Pope, Andreyah, Sanchez-Reyes, Omar B., Eilers, Markus, Opefi, Chikwado A., Ziliox, Martine, Reeves, Philip J., Smith, Steven O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972713/
https://www.ncbi.nlm.nih.gov/pubmed/27376589
http://dx.doi.org/10.1038/nsmb.3257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972713/
https://www.ncbi.nlm.nih.gov/pubmed/27376589
http://dx.doi.org/10.1038/nsmb.3257

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