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Treatment of Acne Keloidalis Nuchae: A Systematic Review of the Literature

Acne keloidalis nuchae (AKN) is a chronic inflammatory condition that leads to fibrotic plaques, papules and alopecia on the occiput and/or nape of the neck. Traditional medical management focuses on prevention, utilization of oral and topical antibiotics, and intralesional steroids in order to decr...

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Autores principales: Maranda, Eric L., Simmons, Brian J., Nguyen, Austin H., Lim, Victoria M., Keri, Jonette E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972740/
https://www.ncbi.nlm.nih.gov/pubmed/27432170
http://dx.doi.org/10.1007/s13555-016-0134-5
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author Maranda, Eric L.
Simmons, Brian J.
Nguyen, Austin H.
Lim, Victoria M.
Keri, Jonette E.
author_facet Maranda, Eric L.
Simmons, Brian J.
Nguyen, Austin H.
Lim, Victoria M.
Keri, Jonette E.
author_sort Maranda, Eric L.
collection PubMed
description Acne keloidalis nuchae (AKN) is a chronic inflammatory condition that leads to fibrotic plaques, papules and alopecia on the occiput and/or nape of the neck. Traditional medical management focuses on prevention, utilization of oral and topical antibiotics, and intralesional steroids in order to decrease inflammation and secondary infections. Unfortunately, therapy may require months of treatment to achieve incomplete results and recurrences are common. Surgical approach to treatment of lesions is invasive, may require general anesthesia and requires more time to recover. Light and laser therapies offer an alternative treatment for AKN. The present study systematically reviews the currently available literature on the treatment of AKN. While all modalities are discussed, light and laser therapy is emphasized due to its relatively unknown role in clinical management of AKN. The most studied modalities in the literature were the 1064-nm neodymium-doped yttrium aluminum garnet laser, 810-nm diode laser, and CO(2) laser, which allow for 82–95% improvement in 1–5 sessions. Moreover, side effects were minimal with transient erythema and mild burning being the most common. Overall, further larger-scale randomized head to head control trials are needed to determine optimal treatments.
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spelling pubmed-49727402016-08-17 Treatment of Acne Keloidalis Nuchae: A Systematic Review of the Literature Maranda, Eric L. Simmons, Brian J. Nguyen, Austin H. Lim, Victoria M. Keri, Jonette E. Dermatol Ther (Heidelb) Review Acne keloidalis nuchae (AKN) is a chronic inflammatory condition that leads to fibrotic plaques, papules and alopecia on the occiput and/or nape of the neck. Traditional medical management focuses on prevention, utilization of oral and topical antibiotics, and intralesional steroids in order to decrease inflammation and secondary infections. Unfortunately, therapy may require months of treatment to achieve incomplete results and recurrences are common. Surgical approach to treatment of lesions is invasive, may require general anesthesia and requires more time to recover. Light and laser therapies offer an alternative treatment for AKN. The present study systematically reviews the currently available literature on the treatment of AKN. While all modalities are discussed, light and laser therapy is emphasized due to its relatively unknown role in clinical management of AKN. The most studied modalities in the literature were the 1064-nm neodymium-doped yttrium aluminum garnet laser, 810-nm diode laser, and CO(2) laser, which allow for 82–95% improvement in 1–5 sessions. Moreover, side effects were minimal with transient erythema and mild burning being the most common. Overall, further larger-scale randomized head to head control trials are needed to determine optimal treatments. Springer Healthcare 2016-07-18 /pmc/articles/PMC4972740/ /pubmed/27432170 http://dx.doi.org/10.1007/s13555-016-0134-5 Text en © The Author(s) 2016 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review
Maranda, Eric L.
Simmons, Brian J.
Nguyen, Austin H.
Lim, Victoria M.
Keri, Jonette E.
Treatment of Acne Keloidalis Nuchae: A Systematic Review of the Literature
title Treatment of Acne Keloidalis Nuchae: A Systematic Review of the Literature
title_full Treatment of Acne Keloidalis Nuchae: A Systematic Review of the Literature
title_fullStr Treatment of Acne Keloidalis Nuchae: A Systematic Review of the Literature
title_full_unstemmed Treatment of Acne Keloidalis Nuchae: A Systematic Review of the Literature
title_short Treatment of Acne Keloidalis Nuchae: A Systematic Review of the Literature
title_sort treatment of acne keloidalis nuchae: a systematic review of the literature
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972740/
https://www.ncbi.nlm.nih.gov/pubmed/27432170
http://dx.doi.org/10.1007/s13555-016-0134-5
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