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Nm23H1 mediates tumor invasion in esophageal squamous cell carcinoma by regulation of CLDN1 through the AKT signaling
Esophageal cancer is a lethal malignancy worldwide. Previously, low expression of metastasis suppressor Nm23H1 and tight junction (TJ) protein claudin-1 (CLDN1) have been known to correlate with poor prognosis in esophageal squamous cell carcinoma (ESCC). However, the molecular interaction between t...
Autores principales: | Kuo, K-T, Chen, C-L, Chou, T-Y, Yeh, C-T, Lee, W-H, Wang, L-S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972901/ https://www.ncbi.nlm.nih.gov/pubmed/27376780 http://dx.doi.org/10.1038/oncsis.2016.46 |
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