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Population genetic processes affecting the mode of selective sweeps and effective population size in influenza virus H3N2
BACKGROUND: Human influenza virus A/H3N2 undergoes rapid adaptive evolution in response to host immunity. Positively selected amino acid substitutions have been detected mainly in the hemagglutinin (HA) segment. The genealogical tree of HA sequences sampled over several decades comprises a long trun...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972962/ https://www.ncbi.nlm.nih.gov/pubmed/27487769 http://dx.doi.org/10.1186/s12862-016-0727-8 |