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Adenomyoepithelioma of the breast with late pulmonary metastases – case report and review of the literature

BACKGROUND: Adenomyoepithelioma (AME) of the breast is a rare tumour of unpredictable clinical behaviour. Most of the tumours are benign with some giving local recurrences or distant metastases. CASE PRESENTATION: We report a case of late lung metastases in a woman with a history of breast adenomyoe...

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Autores principales: Korolczuk, Agnieszka, Amarowicz, Magdalena, Bąk, Kamila, Korobowicz, Elżbieta, Koncewicz, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973092/
https://www.ncbi.nlm.nih.gov/pubmed/27487934
http://dx.doi.org/10.1186/s13019-016-0518-8
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author Korolczuk, Agnieszka
Amarowicz, Magdalena
Bąk, Kamila
Korobowicz, Elżbieta
Koncewicz, Tomasz
author_facet Korolczuk, Agnieszka
Amarowicz, Magdalena
Bąk, Kamila
Korobowicz, Elżbieta
Koncewicz, Tomasz
author_sort Korolczuk, Agnieszka
collection PubMed
description BACKGROUND: Adenomyoepithelioma (AME) of the breast is a rare tumour of unpredictable clinical behaviour. Most of the tumours are benign with some giving local recurrences or distant metastases. CASE PRESENTATION: We report a case of late lung metastases in a woman with a history of breast adenomyoepithelioma. Partial lobectomy was performed for lung lesions and initial diagnosis was epithelial-myoepithelial carcinoma. CONCLUSION: Careful slide’s revision of both breast and pulmonary lesions showed identical microscopic appearance with lung tumour performing more malignant features. Tumour cells in both: breast and pulmonary lesions were positive for cytokeratin and EMA (epithelial cells) and also for SMA, S100 and vimentin (myoepithelial cells). Two years and 7 months follow-up showed no recurrent neoplastic disease in our patient.
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spelling pubmed-49730922016-08-05 Adenomyoepithelioma of the breast with late pulmonary metastases – case report and review of the literature Korolczuk, Agnieszka Amarowicz, Magdalena Bąk, Kamila Korobowicz, Elżbieta Koncewicz, Tomasz J Cardiothorac Surg Case Report BACKGROUND: Adenomyoepithelioma (AME) of the breast is a rare tumour of unpredictable clinical behaviour. Most of the tumours are benign with some giving local recurrences or distant metastases. CASE PRESENTATION: We report a case of late lung metastases in a woman with a history of breast adenomyoepithelioma. Partial lobectomy was performed for lung lesions and initial diagnosis was epithelial-myoepithelial carcinoma. CONCLUSION: Careful slide’s revision of both breast and pulmonary lesions showed identical microscopic appearance with lung tumour performing more malignant features. Tumour cells in both: breast and pulmonary lesions were positive for cytokeratin and EMA (epithelial cells) and also for SMA, S100 and vimentin (myoepithelial cells). Two years and 7 months follow-up showed no recurrent neoplastic disease in our patient. BioMed Central 2016-08-04 /pmc/articles/PMC4973092/ /pubmed/27487934 http://dx.doi.org/10.1186/s13019-016-0518-8 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Korolczuk, Agnieszka
Amarowicz, Magdalena
Bąk, Kamila
Korobowicz, Elżbieta
Koncewicz, Tomasz
Adenomyoepithelioma of the breast with late pulmonary metastases – case report and review of the literature
title Adenomyoepithelioma of the breast with late pulmonary metastases – case report and review of the literature
title_full Adenomyoepithelioma of the breast with late pulmonary metastases – case report and review of the literature
title_fullStr Adenomyoepithelioma of the breast with late pulmonary metastases – case report and review of the literature
title_full_unstemmed Adenomyoepithelioma of the breast with late pulmonary metastases – case report and review of the literature
title_short Adenomyoepithelioma of the breast with late pulmonary metastases – case report and review of the literature
title_sort adenomyoepithelioma of the breast with late pulmonary metastases – case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973092/
https://www.ncbi.nlm.nih.gov/pubmed/27487934
http://dx.doi.org/10.1186/s13019-016-0518-8
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