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Predictive Immunohistochemical Markers Related to Drug Selection for Patients Treated with Sunitinib or Sorafenib for Metastatic Renal Cell Cancer
Targeted drug decisions in metastatic renal cell carcinoma are exclusively made on the basis of clinical criteria. We investigated whether these biomarkers (HIF-1α, HIF-2α, CAIX, VEGF, VEGFR1, VEGFR2, VEGFR3, PDGFB, PDGFRA, PDGFRB, CD31, CD44, bcl-xL, KIT, p21, CXCR4, PTEN, (CSF)-1R, RET, and FLT-3)...
Autores principales: | Ma, Xin, Wang, Lei, Li, Hongzhao, Zhang, Yu, Gao, Yu, Guo, Gang, Liu, Kan, Meng, Qingyu, Zhao, Chaofei, Wang, Dianjun, Song, Zhigang, Zhang, Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973254/ https://www.ncbi.nlm.nih.gov/pubmed/27488093 http://dx.doi.org/10.1038/srep30886 |
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