Metformin Enhances the Therapy Effects of Anti-IGF-1R mAb Figitumumab to NSCLC

The insulin-like growth factor (IGF) signaling system plays a critical role in tumorigenesis, highlighting the potential of targeting IGF-1R as an anti-cancer therapy. Although multiple anti-IGF-1R monoclonal antibody (mAb) drugs have been developed, challenges remain in the validation of the therap...

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Detalles Bibliográficos
Autores principales: Cao, Hongxin, Dong, Wei, Qu, Xiao, Shen, Hongchang, Xu, Jun, Zhu, Linhai, Liu, Qi, Du, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973270/
https://www.ncbi.nlm.nih.gov/pubmed/27488947
http://dx.doi.org/10.1038/srep31072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973270/
https://www.ncbi.nlm.nih.gov/pubmed/27488947
http://dx.doi.org/10.1038/srep31072

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