Cargando…

A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin

Repair of DNA double-strand breaks (DSBs) must be properly orchestrated in diverse chromatin regions to maintain genome stability. The choice between two main DSB repair pathways, nonhomologous end-joining (NHEJ) and homologous recombination (HR), is regulated by the cell cycle as well as chromatin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Janssen, Aniek, Breuer, Gregory A., Brinkman, Eva K., van der Meulen, Annelot I., Borden, Sean V., van Steensel, Bas, Bindra, Ranjit S., LaRocque, Jeannine R., Karpen, Gary H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973294/ https://www.ncbi.nlm.nih.gov/pubmed/27474442 http://dx.doi.org/10.1101/gad.283028.116

Ejemplares similares

Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A
por: Janssen, Aniek, et al.
Publicado: (2019)

Molecular Complexes at Euchromatin, Heterochromatin and Centromeric Chromatin
por: Morrison, Olivia, et al.
Publicado: (2021)

Opposing Roles of FACT for Euchromatin and Heterochromatin in Yeast
por: Takahata, Shinya, et al.
Publicado: (2023)

DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin
por: Jakob, Burkhard, et al.
Publicado: (2011)

Assembly and characterization of heterochromatin and euchromatin on human artificial chromosomes
por: Grimes, Brenda R, et al.
Publicado: (2004)

Replication of the Mammalian Genome by Replisomes Specific for Euchromatin and Heterochromatin
por: Zhang, Jing, et al.
Publicado: (2021)

Targeted Inter-Homologs Recombination in Arabidopsis Euchromatin and Heterochromatin
por: Filler-Hayut, Shdema, et al.
Publicado: (2021)

Chromosome Preference During Homologous Recombination Repair of DNA Double-Strand Breaks in Drosophila melanogaster
por: Fernandez, Joel, et al.
Publicado: (2019)

The Role of Drosophila CtIP in Homology-Directed Repair of DNA Double-Strand Breaks
por: Yannuzzi, Ian, et al.
Publicado: (2021)

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin
por: Lee, Yuh Chwen G., et al.
Publicado: (2020)

Protocol: A Multiplexed Reporter Assay to Study Effects of Chromatin Context on DNA Double-Strand Break Repair
por: Schep, Ruben, et al.
Publicado: (2022)

Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks
por: Brinkman, Eva K., et al.
Publicado: (2018)

The Chromatin of Candida albicans Pericentromeres Bears Features of Both Euchromatin and Heterochromatin
por: Freire-Benéitez, Verónica, et al.
Publicado: (2016)

Repair of DNA Double-Strand Breaks in Heterochromatin
por: Watts, Felicity Z.
Publicado: (2016)

Double-Strand Break Repair Assays Determine Pathway Choice and Structure of Gene Conversion Events in Drosophila melanogaster
por: Do, Anthony T., et al.
Publicado: (2013)

Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae
por: Verzijlbergen, Kitty F, et al.
Publicado: (2009)

Biphasic Euchromatin-to-Heterochromatin Transition on the KSHV Genome Following De Novo Infection
por: Toth, Zsolt, et al.
Publicado: (2013)

Heterochromatin protein 1 (HP1) is associated with induced gene expression in Drosophila euchromatin
por: Piacentini, Lucia, et al.
Publicado: (2003)

Molecular Landscape of Modified Histones in Drosophila Heterochromatic Genes and Euchromatin-Heterochromatin Transition Zones
por: Yasuhara, Jiro C, et al.
Publicado: (2008)

Entropic effect of macromolecular crowding enhances binding between nucleosome clutches in heterochromatin, but not in euchromatin
por: Oh, Inrok, et al.
Publicado: (2018)

Aging impairs double‐strand break repair by homologous recombination in Drosophila germ cells
por: Delabaere, Laetitia, et al.
Publicado: (2016)

Homologues of potato chromosome 5 show variable collinearity in the euchromatin, but dramatic absence of sequence similarity in the pericentromeric heterochromatin
por: de Boer, Jan M, et al.
Publicado: (2015)

Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions
por: Wen, Bo, et al.
Publicado: (2012)

Microscopic Analysis of Heterochromatin, Euchromatin and Cohesin in Cancer Cell Models and under Anti-Cancer Treatment
por: Fischer, Elias Ferdinand, et al.
Publicado: (2023)

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin
por: Truch, Julia, et al.
Publicado: (2022)

Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch
por: Yuita, Hiroshi, et al.
Publicado: (2023)

Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin
por: Lan, Li, et al.
Publicado: (2014)

The Sound of Silence: How Silenced Chromatin Orchestrates the Repair of Double-Strand Breaks
por: Kendek, Apfrida, et al.
Publicado: (2021)

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
por: Schep, Ruben, et al.
Publicado: (2021)

DNA Double-Strand Break Repair: All Roads Lead to HeterochROMAtin Marks
por: Caron, Pierre, et al.
Publicado: (2021)

Karyotype Evolution in 10 Pinniped Species: Variability of Heterochromatin versus High Conservatism of Euchromatin as Revealed by Comparative Molecular Cytogenetics
por: Beklemisheva, Violetta R., et al.
Publicado: (2020)

Long-range heterochromatin association is mediated by silencing and double-strand DNA break repair proteins
por: Kirkland, Jacob G., et al.
Publicado: (2013)

ATM Release at Resected Double-Strand Breaks Provides Heterochromatin Reconstitution to Facilitate Homologous Recombination
por: Geuting, Verena, et al.
Publicado: (2013)

High-resolution mapping of heterochromatin redistribution in a Drosophila position-effect variegation model
por: Vogel, Maartje J, et al.
Publicado: (2009)

Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67
por: van Schaik, Tom, et al.
Publicado: (2022)

Neurodegeneration, Heterochromatin, and Double-Stranded RNA
por: Saldi, Tassa K, et al.
Publicado: (2019)

Genome-wide mapping of DNase I hypersensitive sites reveals chromatin accessibility changes in Arabidopsis euchromatin and heterochromatin regions under extended darkness
por: Liu, Yue, et al.
Publicado: (2017)

Transcription organizes euchromatin via microphase separation
por: Hilbert, Lennart, et al.
Publicado: (2021)

The role of Drosophila mismatch repair in suppressing recombination between diverged sequences
por: Do, Anthony T., et al.
Publicado: (2015)

Focused Ion Microbeam Irradiation Induces Clustering of DNA Double-Strand Breaks in Heterochromatin Visualized by Nanoscale-Resolution Electron Microscopy
por: Lorat, Yvonne, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l5bq1m5b64g9gulik1i14f0hdp