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mTAIL-seq reveals dynamic poly(A) tail regulation in oocyte-to-embryo development

Eukaryotic mRNAs are subject to multiple types of tailing that critically influence mRNA stability and translatability. To investigate RNA tails at the genomic scale, we previously developed TAIL-seq, but its low sensitivity precluded its application to biological materials of minute quantity. In th...

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Detalles Bibliográficos
Autores principales: Lim, Jaechul, Lee, Mihye, Son, Ahyeon, Chang, Hyeshik, Kim, V. Narry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973296/
https://www.ncbi.nlm.nih.gov/pubmed/27445395
http://dx.doi.org/10.1101/gad.284802.116