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Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson's disease alpha-synuclein transgenic mice
α-Synuclein (α-Syn) has a critical role in microglia-mediated neuroinflammation, which leads to the development of Parkinson's disease (PD). Recent studies have shown that bee venom (BV) has beneficial effects on PD symptoms in human patients or 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPT...
Autores principales: | Ye, Minsook, Chung, Hwan-Suck, Lee, Chanju, Hyun Song, Joo, Shim, Insop, Kim, Youn-Sub, Bae, Hyunsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973312/ https://www.ncbi.nlm.nih.gov/pubmed/27388550 http://dx.doi.org/10.1038/emm.2016.49 |
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