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GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR
GPRC5A is an orphan G-protein coupled receptor with an intriguing dual behavior, acting as an oncogene in some cancers and as a tumor suppressor in other cancers. In the pancreatic cancer context, very little is known about GPRC5A. By analyzing messenger RNA (mRNA) expression data from 675 human can...
Autores principales: | Zhou, H, Telonis, A G, Jing, Y, Xia, N L, Biederman, L, Jimbo, M, Blanco, F, Londin, E, Brody, J R, Rigoutsos, I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973341/ https://www.ncbi.nlm.nih.gov/pubmed/27415424 http://dx.doi.org/10.1038/cddis.2016.169 |
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